These unstable molecules are byproducts of your body’s functions. It also holds free radicals in check. Image:ShutterStock. If you are experiencing … herb native to southern Europe that typically grows over 10 feet tall and has red and purple flowers These include ragweed, daisies, marigolds, and chrysanthemums. Milk thistle and compounds derived from it are commonly used as herbal supplements for liver problems, but study results are mixed. People with diabetes should use caution. Studies show that silymarin may help ease inflammation and promote cell repair. The terms milk thistle and silymarin are often used interchangeably, even though they aren’t exactly the same thing. … de Avelar CR, Pereira EM, de Farias Costa PR, et al. Its resources include publications (such as Dietary Supplements: What You Need to Know), fact sheets on a variety of specific supplement ingredients and products (such as vitamin D and multivitamin/mineral supplements), and the PubMed Dietary Supplement Subset. Over the years the liver gets bogged down by heavy metals, fatty foods, alcohol and chemicals, and becomes sluggish. This supplement is … Swallow the capsule or pill with a glass of water. Silymarin is a flavonoid believed to have antioxidant properties.Milk thistle is sold as an oral capsule, tablet, powder and liquid extract. One of the liver’s most important functions is defending against toxins found in our environment. ODS seeks to strengthen knowledge and understanding of dietary supplements by evaluating scientific information, supporting research, sharing research results, and educating the public. Milk thistle is native to Europe’s Mediterranean region. tty (for deaf and hard-of-hearing callers): Email: info@nccih.nih.gov (link sends e-mail). The milk thistle extract is usually prescribed to treat mushroom poisoning, alcoholic cirrhosis, chronic hepatitis, drug and alcohol-induced liver damage, acute viral hepatitis as well as fatty liver and many doctors consider it the most important supplement when it comes to maintaining a healthy liver. Supplements & Your Liver - Does Milk Thistle Help Your Liver? Medical research on milk thistle and liver health has led to mixed results. Accessed at naturalmedicines.therapeuticresearch.com on April 1, 2020. Duplication is encouraged. But they can harm healthy cells and lead to health issues. For example, a comprehensive study in 2016 found that milk thistle can improve diet-induced liver damage. Laboratory studies suggest that milk thistle or some of its compounds have protective effects on the liver… U.S. Department of Health & Human Services, 9000 Rockville Pike Bethesda, Maryland 20892, U.S. Department of Health and Human Services. How Much Milk Thistle to Take to Repair Liver? Milk thistle has been used as a natural remedy to treat liver problems, including fatty liver disease, for centuries. Generally, it’s safe to take milk thistle in recommended doses. Milk thistle is a natural herb with antioxidant and anti-inflammatory properties. Often considered a weed, it has been used for hundreds of years as a natural, herbal way to treat liver and gallbladder diseases. Natural Medicines website. It’s sometimes called silymarin, which is one of the main components of the plant’s seeds. Although preliminary laboratory studies found that silymarin exerted antiviral, anti-inflammatory, antioxidant, and liver-protective effects, researchers still don’t fully understand why, and those benefits were not seen in clinical trials (studies in people) of milk thistle for liver … Milk thistle may have been combined with other plants or extracts in a specific preparation to treat these conditions. We encourage you to discuss any decisions about treatment or care with your health care provider. These toxins lurk in the food we eat, prescription drugs, and even the clothing we wear! People mainly use the supplement to treat liver conditions. Some people have reported nausea, gas, diarrhea, or loss of appetite. Milk thistle is a plant named for the white veins on its large prickly leaves.One of the active ingredients in milk thistle is silymarin, which is extracted from the plant's seeds. News Release, University of California Santa Cruz. Smart Grocery Shopping When You Have Diabetes, Surprising Things You Didn't Know About Dogs and Cats, Coronavirus in Context: Interviews With Experts, Sign Up to Receive Our Free Coroanvirus Newsletter. Is This an Emergency? But is it really good for you, and can it really help your liver? Leptin Hormone & Supplements: Do They Work for Obesity & Weight Loss. Milk Thistle Table 5: Clinical Studies on Liver Disease & Liver Health; Study Information Outcome; Randomized, placebo-controlled, double-blind 2-year prospective clinical trial (). Milk thistle is one of the most powerful supplements available today that helps detox the liver, protect the body from free radical damage, and reduce inflammation. Milk thistle provides many benefits to your overall health, but specifically supports liver function and liver health. Small Business Research Grant Program (SBIR), About Research Training and Career Development, Training Grant Application, Review, and Award Process, Integrative Medicine Research Lecture Series, Division of Extramural Research Sponsored by NCCIH, Division of Intramural Research Conducted at NCCIH, Know the Science: How Medications and Supplements Can Interact, Know the Science: 9 Questions To Help You Make Sense of Health Research, How To Find Information About Complementary Health Approaches on PubMed, Dietary Supplements: What You Need to Know. Tajmohammadi A, Razavi BM, Hosseinzadeh H. If the leaves are ripped or crushed, a milky white liquid oozes out. A service of the National Library of Medicine, PubMed® contains publication information and (in most cases) brief summaries of articles from scientific and medical journals. There have been numerous studies suggesting milk thistle can support different aspects of liver health. A major study found that people with hepatitis C didn’t benefit even from higher-than-normal doses of silymarin. This plant is named for the white lines that streak across its green leaves. Liver related conditions indicating the use of milk thistle are varied, including, but not limited to: Alcoholic cirrhosis Chronic active hepatitis Drug and alcohol induced liver damage Acute viral hepatitis Fatty … 170 adult and child patients with cirrhosis of the liver (both alcoholic and non-alcoholic causes) (). This may help ease symptoms … Basically, it depends on one’s condition. It may affect how some medications work, including. Usually the supplements contain 80%of milk thistle and some high quality products contain 95% of the original herb. Although milk thistle is most often used for liver conditions, such as hepatitis and cirrhosis, the herb is believed some to prevent or treat high cholesterol, diabetes, heartburn, upset stomach … Together, you can make shared, well-informed decisions. It’s not known whether milk thistle is helpful for other conditions. Milk Thistle Liver Detox Milk Thistle Liver Detox is specially formulated to support overall liver health, essential to the body's overall health. Jarrow Formulas Milk Thistle (Silymarin Marianum), Promotes Liver Health, 150 mg per Capsule, 200 Count. The Clearinghouse does not provide medical advice, treatment recommendations, or referrals to practitioners. Although some studies have shown positive results on milk thistle for people with chronic hepatitis C virus (HCV) infection, the overall research does not show a benefit. Medical research on milk thistle and liver health has led to mixed results. All rights reserved. The COVID-19 outbreak is a rapidly evolving situation. Background Milk thistle is native to Europe and was introduced into North America by early colonists. WebMD does not provide medical advice, diagnosis or treatment. In the United States, it’s one of the most commonly used herbal supplements for liver issues. Other people have reported a headache or itchiness after they take it. Milk thistle comes in powder, capsule, pill, or liquid extract forms. Some of the studies have been of poor quality, too. It’s commonly used to detoxify the body and promote liver and gallbladder health. There’s conflicting research on the benefits of milk thistle for liver health. Amanita phalloides is better known as the death cap for good reason. Researchers theorize that the active ingredient in milk thistle, silymarin, helps the liver … Results from clinical trials of milk thistle for liver diseases have been conflicting or haven’t been clinically meaningful. Milk Thistle. It may have protective effects on the liver, preventing damage. One of the most common uses of milk thistle is to treat liver problems. What Is Complementary, Alternative, or Integrative Health? Milk thistle is found throughout the eastern United States, California, South America, Africa, Australia, and Asia. Researchers found no changes in virus levels or quality of life in people who took the milk thistle, compared with those who took a placebo. This publication is not copyrighted and is in the public domain. Little is known about whether it’s safe to use milk thistle during pregnancy or while breastfeeding. People who have diabetes should talk to their doctor before they take milk thistle because it may lower blood sugar. The mention of any product, service, or therapy is not an endorsement by NCCIH. Website: https://pubmed.ncbi.nlm.nih.gov/. University of Rochester Medical Center: “Milk Thistle.”, National Center for Complementary and Integrative Health: “Hepatitis C and Dietary Supplements,” “Milk Thistle.”, Lancet Oncology: “Milk thistle: early seeds of potential.”, Huntington’s Outreach Project For Education, at Stanford: “About Free Radical Damage.”, Journal of Natural Products: “Silymarin Suppresses Cellular Inflammation By Inducing Reparative Stress Signaling.”, Journal of the American Medical Association: “Effect of silymarin (milk thistle) on liver disease in patients with chronic hepatitis C unsuccessfully treated with interferon therapy: a randomized controlled trial.”, Centers for Disease Control and Prevention It is not intended to substitute for the medical expertise and advice of your health care provider(s). Milk thistle is thought to exert its protective effects on the liver through the promotion of liver cell growth and the prevention of oxidation and inflammation in the liver. 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