When should we eat? Silybum Marianum Health Benefits Silybum marianum is used to treat dyspepsia (heartburn), and is especially effective when used in combination with other plant extracts, such as lemon balm, angelica, peppermint and chamomile. The anti-angiogenic activity of this herb is evident in the human umbilical vein endothelial cells in a dose-dependent manner. Milk thistle (Silybum marianum) is a flowering herb known for its important medicinal properties. Mediterranean region. The results of this study indicated that Silibinin could strongly inhibit the growth of HepG2 and Hep3B cells. What is Milk-Thistle Herb? Mediterranean regions, Meadows, Borders of forests. Milk thistle is commonly used as a home remedy to treat liver problems, often under the presumption that it will "detoxify" the liver. One active substance known as silymarin has strong antioxidant properties and has been shown to inhibit the growth of human prostate, breast, and cervical cancer cells in test tubes. In the middle ages, the leaves were used in salads, but these days … Silybum marianum is the more technical name for milk thistle. The 18+ Benefits of Milk Thistle (Silybum marianum) and Mechanisms Milk Thistle: More than Just a Liver Support Milk thistle has been used for over 2000 years as a remedy for ailments of the liver, kidney and gallbladder. Holarrhena Antidysenterica (Pubescens) – Kurchi (Kutaj), Amazing Benefits of Fennel Seeds (Saunf) that You Should Know, Yarsagumba (Cordyceps Sinensis – Ophiocordyceps Sinensis). alcoholic fatty liver, liver poisoning. Silymarin is a flavonoid believed to have antioxidant properties.Milk thistle is sold as an oral capsule, tablet, powder and liquid extract. Some ask, what are the benefits of Milk Thistle Seed. Milk thistle also contains other important nutrients such as vitamin E and vitamin C. It also contains a high amount of lipophilic compounds that act as a bioflavonoid antioxidant. Milk Thistle Benefits for Dogs ... Silybin, and Silydianin, which is collectively known as Silybum marianum. The three main compounds taken from the plant — silybin, silydianin, and … Milk thistle is a weed, which grows commonly in California and other parts of the world having a warm climate. (1). The efficacy of Silibin present in this herb against the human hepatocellular carcinoma cells was studied. is the most researched plant for the treatment of liver disease. It can reduce inflammation (important for people with liver inflammation or hepatitis), and has potent antioxidant effects. Having been in use as a herbal remedy for over 2000 years, milk thistle is now making a comeback as a popular health aid, and with good reason. Milk Thistle (Silybum marianum) The medicinal use of milk thistle can be traced back thousands of years to the times of the Greek and Roman Empires. A native plant to Southern Europe, the Middle East, and Asia, milk thistle is derived from compounds found in Silybum marianum, a plant that’s in the same family as sunflowers and daisies. The seeds contain silymarin, a group of compounds said to have antioxidant and anti-inflammatory effects. Data published in Phytotherapy Research indicated that 400 mg per day of a Milk thistle (Silybum marianum (L.)) extract for 12 weeks led to statistically less frequent and less severe hot flashes. Silymarin acts as an antioxidant and reduces the free radical production in the body. The left figures (A,C,E) describe measurements of plants grown under normal conditions (20°/10°C d/n). It is composed of 3 isomer flavonolignans including silybin, silychristin, and silydianin that are collectively called Silymarin. Manna SK Silymarin [MILK THISTLE] suppresses TNF-induced activation of NF-kappa B, c-Jun N-terminal kinase, and apoptosis. Silymarin also has shown benefit in patients with Alzheimer's disease, Parkinson's disease, and cerebral ischemia. ... [Effect of Silybum marianum oil and legalon on lipid peroxidation and liver antioxidant systems in rats intoxicated with carbon tetrachloride]. Milk thistle (Silybum marianum L. Do not take carduus marianum, holy thistle, lady's thistle, legalon, Marian thistle, Mary thistle, silibinin, silybin, silybum marianum, silymarin, or St Mary thistle if you are allergic to milk thistle or any ingredients contained in this drug. It has been used for thousands of years as a herbal remedy for a variety of ailments, particularly for the liver. Shin S, Lee JA, Kim M, Kum H, Jung E, Park D. Anti-glycation activities of phenolic constituents from Silybum marianum (milk thistle) flower in vitro and on human explants. The following purported benefits are only supported by limited, low-quality clinical studies. But the benefits, if any, are small. The common symptoms of cirrhosis include jaundice or yellowish discoloration of the skin, recurrent episodes of nausea and vomiting, pain in the abdomen, constipation or diarrhea, and loss of appetite. Scientific Name : Silybum marianum Other names: Silymarin, Marian Thistle, Mediterranean Thistle, Mary Thistle, Holy Thistle, Silybum Marianum Milk thistle Plant description . Psoriasis. It helps to detoxify the body, especially the blood and liver. This herb is a must for cleansing and for anyone with any sort of liver dysfunction or exposure to toxins. Milk thistle, or Silybum marianum, is a plant used to treat liver disease and breastfeeding problems, among others. Milk thistle, Mary thistle or silymarin (Silybum marianum) is a herbaceous annual or biennial flowering plant of … This helps to prevent the oxidative degradation of the lipids thus preventing the damage to the hepatic cells. Despite the fact that milk thistle is widely used in the treatment of hepatitis (particularly hepatitis C), results from four viral hepatitis studies were contradictory. Milk thistle's estrogen-like effect may also have some usefulness for men with prostate cancer. Suplement diety Silybum Marianum nie może być stosowany jako substytut zróżnicowanej diety. Milk thistle is one of the most commonly used medicinal plants in the world and is also the number one recommended natural herb for liver health. Milk thistle, Mary thistle or silymarin (Silybum marianum) is a herbaceous annual or biennial flowering plant of … In Europe, milk thistle is a prescribed medication. Lowering cholesterol. The X axis shows three categories of patch types: Green, patch of a green mutant; Var-G, green patch on a variegated leaf; Var-W, white patch on a variegated leaf. It also offers a rich source of flavonoids. Silymarin in Milk Thistle also produces an antifibrotic activity. The anti-cancer potential of Milk Thistle was evaluated during research. Disclaimer: Information provided on this website is not intended to diagnose, prevent, treat, or cure any disease. It was also found to exert a relatively stronger cytotoxic effect on the Hep3B cells that was associated with the induction of apoptosis. It has been used for thousands of years for the treatment of liver problems. It is one of the oldest herb and has proved its uses and benefits in treating numerous disorders. While more scientific studies are needed to prove the efficacy of milk thistle to treat or prevent any condition, there is a fountain of anecdotal evidence to support its use. It is a complex mixture of several polyphenolic molecules that includes seven flavonolignans (isosilybin A, isosilybin B, silybin A, silybin B, isosilychristin, silychristin, and silydianin) and a flavonoid (taxifolin). Milk Thistle possesses hepatoprotective properties. These effects are probably related to inhibition of activation of NF-kappa B and the kinases. For the uninitiated, milk thistle (Silybum marianum) is a tall herb with large purple flowers and small hard seed-like fruits – called achenes – to which milk thistle owes its medicinal properties. It is effective at reversing the damaging effects of pesticides in our food supply, and heavy metals in the water supply, thus preventing the occurrence of cirrhosis. This results in an inability of the cancer cells to survive thus leading to their destruction. Liver disease. Silymarin acts as an antioxidant and reduces the free radical production in the body. Milk thistle, known as 'Doodh Patra' has medicinal properties. Due to these components, milk thistle has anti-inflammatory properties, and it helps treat liver diseases in dogs, cats, ferrets, and even humans. Further studies in people are needed. Milk thistle, or silybum marianum, has been used as a herbal healer since ancient Greek times. (3), Get notification for new articles in your inbox. Preliminary laboratory studies also suggest that active substances in milk thistle may have anti-cancer effects. Gaertn.) Milk thistle is a wild, commonly found plant with wide range of possible health benefits. This study indicated that the use of Milk Thistle could be beneficial in the management of hepatitis C. (2). The study was conducted on 55 patients diagnosed with hepatitis C. The participants were administered 630 mg of Silymarin per day for 24 weeks. What is milk thistle? The use of Milk Thistle can be beneficial in the management of cancer. The results of this study showed a statistically significant difference in the mean ALT and AST levels before and after the treatment. Silybum marianum is used to treat dyspepsia (heartburn), and is especially effective when used in combination with other plant extracts, such as lemon balm, angelica, peppermint and chamomile. It can be used in the treatment of cancer. In traditional knowledge, people have used S. marianum for liver disorders such as hepatitis, liver cirrhosis and gallbladder diseases. It can also help to reduce the symptoms of bacterial hepatitis. RFI Media Ltd | Please do not copy our content without permission | Website by Hallnet. Dosage of Milk Thistle? These results confirmed the biological efficacy of Milk Thistle that could help in the treatment of hepatocellular carcinoma. Read more about the prescription drug MILK THISTLE (Silybum marianum) - ORAL. The following purported benefits are only supported by limited, low-quality clinical studies. The most-known and well-established health benefit of milk thistle is how it supports your liver. The ancient philosophers Pliny and Galen both praised the herb for liver cleansing. It can reduce the progress of cancer. Gaertn.) 2015;20(3):3549-3564.25706757 Health Benefits of Milk Thistle. The X axis shows three categories of patch types: Green, patch of a green mutant; Var-G, green patch on a variegated leaf; Var-W, white patch on a variegated leaf. Silybum marianum, commonly known as Milk thistle or St Mary’s thistle, is a herbal remedy that is commonly used to support liver health. It also acts as a galactagogue and promotes the flow of milk. It may also occur due to the inflammation of the liver following bacterial or viral hepatitis, and the use of hepatotoxic medications. Silymarin occurs in milk thistle fruit and seeds, and helps shield skin from the visible effects of UV light exposure (of course, you still need a broad spectrum sunscreen). (Mealtimes in Ayurveda), Recommended and Restricted Vegetables for Salad, Types of Foods in terms of Ease of Digestion, Pineapple Sage (Salvia Elegans) Health Benefits, Dosage & Side Effects. The demulcent action of this herb helps to soothe the mucus membranes in the body affected due to the inflammatory changes. One observational research concluded that a topically-applied, silymarin-based skin cream effectively encourages healthy skin. Silybum marianum (holy thistle, lady’s thistle, milk thistle, St. Mary’s thistle) has been used to treat liver problems, such as hepatitis, and prostatic cancer. The use of this herb is recommended for the patients suffering from cancer. It can reduce inflammation (important for people with liver inflammation or hepatitis), and has potent antioxidant effects. Milk thistle (Silybum marianum L. It can cause suppression of the IGF-receptor signaling and EGFR-MAPK/ERK1/2 signaling. Some found improvements in liver enzyme activity while others failed to detect these benefits. Ethnopharmacological relevance: Silybum marianum (L.) Gaertn. For Ptolemy's town of Corsica, see Bonifacio, for the plant S. marianum, see Silybum marianum. The seeds and fruits of SM contain a flavonolignan complex called silymarin, the active compounds of which include silybin, isosilybin, silychristin, dihydrosilybin, silydianin, and so on. Silybum marianum (holy thistle, lady’s thistle, milk thistle, St. Mary’s thistle) has been used to treat liver problems, such as hepatitis, and prostatic cancer. Milk thistle seed (Silybum marianum) has a history dating back over two thousand years as a favorite among herbalists for its positive effects on the liver and gallbladder. Some preliminary research has suggested that milk thistle may be as effective as the common medication fluoxetine in the treatment of obsessive-compulsive disorder. 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